Clinical Trial Protocol Registry

Trial information

Effect of NT-proBNP guided treatment of Chronic Heart Failure (PRIMA Study).

Status:
No longer recruiting
Protocol number:
2003 B131
Company division:
Diagnostics
Official Scientific Title:
Can pro-brain natriuretic peptide guided therapy of chronic heart failure improve heart failure morbidity and mortality?
Brief summary:
This study will determine whether NT-proBNP guided treatment of chronic congestive heart failure to an individually pre-defined target value will reduce heart failure-related morbidity and mortality compared to therapy guided by standard clinical judgement.
Study type:
Interventional; Randomized; Open Label; Parallel study
Conditions:
  • Congestive Heart Failure
Intervention type:
Diagnostic Test
Intervention name:
ELECSYS®proBNP
Inclusion criteria:
  • adult patients, ≥18 years of age;
  • hospital admission for congestive heart failure;
  • elevated NT-proBNP levels on admission.
Exclusion criteria:
  • life-threatening cardiac arrhythmias;
  • severe lung disease;
  • patients undergoing hemodialysis or CAPD;
  • urgent intervention;
  • presence of life-threatening disease.
Gender:
Males or Females
Age limits:
Min: 18Years Max: N/A (No limit)
Accepts healthy volunteers:
No
Anticipated start date:
May, 2004
Trial registration date:
22.08.2007
Date last updated:
07.02.2008
This trial was conducted at the following locations:
Netherlands
  • Amsterdam
  • Delft
  • Maastricht
  • Rotterdam
  • Utrecht
  • Venlo

Link to trial result

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